On January 7, 2025, China's National Health Commission updated the termination review list for new food ingredients. The PQQ disodium salt, produced by fermentation using the Hyphomicrobium denitrificans MQ004-2 strain by Hubei Magic Health Technology Co., Ltd. (hereinafter referred to as “Maiggic”), was included in the list. The review concluded that it is substantially equivalent to the PQQ disodium salt announced in the 2023 No. 8 notice. Except for the production process, other requirements align with those of the already announced PQQ disodium salt.

Recently, CIRS supported Zhuhai Long Health Biotechnology (hereinafter “Long Health”) in achieving Self-GRAS notification for its 2’-Fucosyllactose (2’-FL), a key component of its HMOs product line. It not only underscores Long Health's strong R&D capabilities and outstanding product quality, but also marks a significant advancement for the company in its expansion into the global nutrition and health market. Additionally, it serves as a powerful testament to CIRS's professional service capabilities.

On February 10, 2025, National Health Commission of the People’s Republic of China (NHC) issued an announcement (No. 1 of 2025) for “Three New Foods” with 20 products approved, including 5 new food raw materials, 8 new food additives, and 7 food-related products.

In the wave of globalization in the food industry, innovation and safety are inseparable. An increasing number of companies are actively pursuing the FDA GRAS notifications for new food ingredients. Unlike self-GRAS, the FDA GRAS require the formation of GRAS evaluation materials, and when GRAS materials are submitted to the FDA, the FDA issue the inventory notices on its official website and updates information periodically. The latest update to this inventory was on January 7, 2025.

According to the European Food Safety Authority (EFSA) and the Official Journal of the European Union, in the last quarter of 2024, EFSA published assessment results for 5 Novel Foods (NF), including the application for 2 new NF and the modification for 3 novel food already authorized. Additionally, EFSA requested scientific and technical assistance as regards the evaluation of 1 Novel Food.